Active Bio-decon Pass Through Chambers

Pass Through Chambers for aseptic transfer of materials in the cleanroom

Active Bio-Decon Pass Through Chambers can be used for multiple applications, such as aseptic transfer of materials into cleanrooms or decontamination of equipment from BSL-1 through 4 organisms prior to extraction from the facility.

In both cases, materials are sterilized in the Pass Through Chambers by means of the integrated VPHP system.

Available downloads:
  • AB-PTC - Brochure

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Guaranteed asepsis

The AB-PTC assures the highest air quality of the isolated environment thanks to:
– an engineered filtration system composed by High-Efficiency Particulate Air (H14) flow and exhaust filters;
– HYPER, Tema Sinergie’s integrated Vapour Phase Hydrogen Peroxide (VPHP) bio-decontamination system for very fast bio-decon cycle
– inflatable seals made of FDA-approved White Silicon
The integrated ventilation system of the chamber guarantees a pressure cascade between the adjoining rooms and the chamber itself. This cascade preserves the asepsis of the materials after the termination of bio-decontamination process prior to extraction into the cleanroom.


Maximizing operator protection is a key feature when handling BSL-1 through 4 organisms. AB-PTC assures the maximum safety thanks to the following features:
– HYPER, an integrated VPHP system for the decontamination of materials prior to extraction from the BSL facility
– pressure control strategy to prevent back flow of air the BSL and non BSL boundaries.
– bio-sealed doors and sheathings to avoid any leak between BSL and non BSL boundaries.
The AB-PTC is therefore the perfect adaptable solution to decontaminate equipment/materials prior to taking it out of a BSL facility, to avoid leak of potentially hazardous organisms towards the external areas.

Automatic leak test

The AB-PTC is equipped with a routine automatic leak testing system which performs an independent leak test cycle for each chamber according to the pressure change method (5.2) ISO 10648-2:1994(E).

Ease of maintenance

A remote control module made of AISI 304 stainless steel, containing electrical and pneumatic components, allows direct access for all maintenance operations.
A Virtual Private Network (VPN) connection allows a secure and private communication via Internet network and provides remote access and assistance, updates and maintenance any time, everywhere.


AB-PTC is available in different standard dimensions, including Walk-In models.


The AB-PTC can also be upgraded with an Integrated Supervisory Control And Data Acquisition (SCADA) – iFIX with Historian Data Management Software (DMS) from GE Digital.
DataWall, a software application developed by Tema Sinergie for data management, is also available upon request.


Thanks to the new sustainable low voltage ventilation fans, the isolator has a very low energy consumption throughout its life.


  • Fully PLC controlled
  • Integrated VPHP generator (HYPER) and distribution circuit
  • VPHP resistant relative humidity and temperature (rH%+T) sensor
  • View/Access panel latches with integrated safety switches
  • LED lighting system
C.F., P.IVA, VATn. IT00970310397
Business Register of Ravenna n. 00970310397  |  R.E.A. 111877
RAEE IT08020000002755
Capital Stock € 2.000.000,00 paid-up