CRP Compact

Automatic radiopharmaceutical dispensing unit for open and closed vials

CRP Compact is a system for the automatic dispensing of radiopharmaceuticals and the automated latching of open and closed vials under sterile conditions, compliant with EU GMP Annex 1 regulations.

Safe, compact, and extremely precise, the system allows for the dispensing of a wide range of radiopharmaceuticals, with no limitations on concentration and volume, minimizing the need for any operator interventions. It can work on both open and closed vials, and handle both crimped and push-fit caps.

CRP Compact and its interface managing software are supplied as promptly validated for pharmaceutical purposes.

Available downloads:
  • 26-CRP-Compact-Rev00_24.pdf

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Two versions available

CRP Compact

Developed for dispensing radiopharmaceuticals in open vials, with rubber stopper and crimped aluminum ring capping. An optional piercing module allows the unit to work with closed vials as well.


CRP Compact plus

Developed for dispensing radiopharmaceuticals in open vials, with subsequent rubber stopper and either a crimped aluminum ring capping or push-fit capping system.




The dispensing process starts from a base solution, originating from the synthesis module, and ends with a closed vial containing the required volume and activity of the radiopharmaceutical being processed. The system automatically performs the following operations:

  • Measuring both total and specific activity delivered by the synthesis module.
  • Diluting the main vial to the required specific activity.
  • Filling open or closed vials, controlling the volume, using a built-in high precision electronic scale.
  • Plugging and crimping the filled vial (if using open vials).

Customized Workflows

The system offers the chance to design customized process flows based on different production needs, with the integration of custom kits. This feature makes CRP Compact the ideal solution for facilities in need of implementing specific workflows, such as CDMO (Contract Development and Manufacturing Organization) companies.


It can process most of the vials currently available on the market, and allows to change the kind of vial even inbetween two consecutive batches on the same production cycle.


It can dispense both open and closed vials, as well as manage different capping strategies, such as push-fit caps or rubber stoppers with crimped aluminum rings.

Dispensing without volume limitations

It allows for handling bulk vials on input without volume and concentration limitations, while also enabling precise dispensing of both high and micro-volumes on output.

Available downloads:
  • CRP Compact - Brochure

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Main Features


Extremely high dispensing precision, with deviation from the target volume (weight) guaranteed to be less than 1% thanks to the integrated high-precision scale.


It can be used for dispensing a wide range of radiopharmaceuticals in vials, in compliance with current GMP.


The whole radiopharmaceutical dispensing process is automated, minimizing the need for any operator interventions.


Thanks to its compact dimensions, it can be installed in any type of shielded laminar flow cell equipped with a well for the calibrator and telemanipulator.


CRP installed around the world

Related Articles

CRP Compact Plus, the answer to different GMP dispensing needs of radiopharmaceuticals

Tema Sinergie introduces CRP Compact Plus, the new version of the well-known and consolidated radiopharmaceutical dispenser specific for vials with Push-Fit caps.
Available downloads:
  • CRP Compact - Brochure

Are you interested in this product?

C.F., P.IVA, VATn. IT00970310397
Business Register of Ravenna n. 00970310397  |  R.E.A. 111877
RAEE IT08020000002755
Capital Stock € 2.000.000,00 paid-up