Quality
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Minimizing dose to the whole breast volume, heart and lungs
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Confidence in targeting accuracy
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Tailor-made solutions designed around your needs.
Start a custom project
Tailor-made solutions designed around your needs.
Start a custom project
Tailor-made solutions designed around your needs.
Start a custom project
Tailor-made solutions designed around your needs.
Start a custom project
Tailor-made solutions designed around your needs.
Start a custom project
Tailor-made solutions designed around your needs.
Start a custom project
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Comprehensive support throughout the entire project lifecycle.
Discover our services
Comprehensive support throughout the entire project lifecycle.
Discover our services
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Discover more about the Tema Sinergie Group and its international presence.
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Discover more about the Tema Sinergie Group and its international presence.
Learn more about the CompanyDiscover more about the Tema Sinergie Group and its international presence.
Learn more about the Company
Discover more about the Tema Sinergie Group and its international presence.
Learn more about the Company
Discover more about the Tema Sinergie Group and its international presence.
Learn more about the CompanyGammaPod™
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The world’s first stereotactic radiotherapy system optimized for treating breast cancer.
GammaPod™ is a new solution designed to deliver non-invasive, highly conformal treatments, with the potential to drastically shorten the course of radiation therapy and limit the doses to the entire breast, heart, and lungs.
Born from the vision of extending the dosimetric benefits of stereotactic radiation therapy to patients undergoing breast-conserving treatment, GammaPod™ is the precision tool that offers the potential to change the way early-stage breast cancer is managed.
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Distributed by Tema Sinergie
overview
Healthcare—and cancer care in particular—is increasingly favoring models that promote high-quality care at lower per-capita costs, while achieving high levels of satisfaction among patients with early-stage breast cancer.
Technologies such as GammaPod™ have the potential to revolutionize the management of localized breast cancer and create real value for patients, clinical centers, and the healthcare system as a whole.
Minimizing dose to the whole breast volume, heart and lungs
Confidence in targeting accuracy
Noninvasive immobilization and treatment
Automated prone positioning
Shortening treatment to between one and five fractions
Improving patient throughput
Fewer visits to the clinic
Once daily treatments
overview
The exceptional features of GammaPod™ help improve clinical outcomes and significantly reduce side effects.
It targets the tumor precisely using highly conformal radiation therapy, maximizing the treatment's effectiveness.
This advanced technology enables a completely non-invasive treatment, eliminating the need for surgery.
It significantly reduces the duration of radiation therapy compared to conventional approaches.
It minimizes radiation exposure to the entire breast, heart, and lungs, thereby reducing side effects.
With GammaPod™, radiation oncologists have a new tool for delivering ultra-accelerated courses of adjuvant stereotactic partial breast irradiation, reducing tumor bed boosts to a single fraction for patients receiving whole breast irradiation and neoadjuvant treatments at ablative dose levels.
Features
GammaPod™ is the first stereotactic radiation therapy system specifically designed for breast cancer.

The ability to safely and confidently deliver a focal dose of radiation to a target within the breast is giving clinicians the opportunity to take breast radiotherapy to new levels.
With GammaPod™, radiation oncologists have a new tool for delivering ultra-accelerated courses of adjuvant stereotactic partial breast irradiation, reducing tumor bed boosts to a single fraction for patients receiving whole breast irradiation and neoadjuvant treatments at ablative dose levels.
How It Works
GammaPod uses a multi-source cobalt-60 system.
During treatment, the system rotates continuously, generating thousands of different beam entry angles that converge to create a single intense focal point, delivering the entire dose to the target while sparing the surrounding healthy tissue.
The 25-mm and 15-mm collimators change dynamically during treatment.
At the same time, the table’s movement allows the target to be moved through the focal spot in three dimensions, enabling true dynamic dose painting.
In this way, the entire prescribed dose is concentrated on the target, ensuring maximum treatment efficacy and minimizing exposure of the surrounding healthy tissues as much as possible.

Stereotactic radiation therapy requires a high degree of precision to ensure accurate dose delivery.
GammaPod uses a custom-designed stereotactic positioning and localization system called the “Breast Cup System,” which provides secure breast immobilization. It is a first-of-its-kind vacuum-assisted dual-cup system that adheres noninvasively to the breast.
The dual-cup design of the GammaPod™ Breast Cup System allows, with a dedicated suction pump, the air between the cups to be evacuated, ensuring immobility and allowing the breast to be separated from other vital tissues.

Patients are custom fit with the appropriately sized inner cup
Inner cup is joined via a silicone flange to a rigid outer cup containing an embedded stereotactic fiducial wire
Adhesive on the flange helps the device adhere to the patient
Attached suction pump evacuates the air from between the cups to provide a stable immobilization.
Clinical trials have found that prone positioning for breast cancer radiotherapy offers multiple benefits.1 The affected breast naturally falls away from chest wall and treatments can be designed to limit dose to the heart and lungs.
The GammaPod™ uses prone patient loaders in the imaging and treatment rooms to quickly and comfortably set up patients in the prone position. Providing reproducible setup at the time of imaging and treatment obviates the need for in-room image guidance.

Patients step onto the loader wearing the breast cup, which fits through an aperture in the couch and is securely docked in place
Smooth rotation of the couch seamlessly moves patients from the standing to prone position
For the Imager Loader, the CT table receives the couch and patient, which is then positioned for scanning
For the Treatment Loader, the GammaPod receives the couch and patient, which is then positioned for treatment.
The GammaPod™ treatment planning system (TPS) uses sophisticated Monte Carlo dose calculations, the gold standard in radiotherapy, to create a dynamic travel path along which the couch will during the delivery of the prescribed dose.
To accommodate the scan-plan-treat clinical workflow, the TPS provides clinicians with tools for quickly creating a new treatment plan each day based on changes to the target and anatomy.
Single-click localization of the stereotactic fiducial wire
Intuitive contouring tools for defining the GTV with interpolation between image slices
Easy creation of uniform margin expansion to define PTV
Rapid optimization based on plan goals

The ability to safely and confidently deliver a focal dose of radiation to a target within the breast is giving clinicians the opportunity to take breast radiotherapy to new levels.
With GammaPod™, radiation oncologists have a new tool for delivering ultra-accelerated courses of adjuvant stereotactic partial breast irradiation, reducing tumor bed boosts to a single fraction for patients receiving whole breast irradiation and neoadjuvant treatments at ablative dose levels.
How It Works
GammaPod uses a multi-source cobalt-60 system.
During treatment, the system rotates continuously, generating thousands of different beam entry angles that converge to create a single intense focal point, delivering the entire dose to the target while sparing the surrounding healthy tissue.
The 25-mm and 15-mm collimators change dynamically during treatment.
At the same time, the table’s movement allows the target to be moved through the focal spot in three dimensions, enabling true dynamic dose painting.
In this way, the entire prescribed dose is concentrated on the target, ensuring maximum treatment efficacy and minimizing exposure of the surrounding healthy tissues as much as possible.

Stereotactic radiation therapy requires a high degree of precision to ensure accurate dose delivery.
GammaPod uses a custom-designed stereotactic positioning and localization system called the “Breast Cup System,” which provides secure breast immobilization. It is a first-of-its-kind vacuum-assisted dual-cup system that adheres noninvasively to the breast.
The dual-cup design of the GammaPod™ Breast Cup System allows, with a dedicated suction pump, the air between the cups to be evacuated, ensuring immobility and allowing the breast to be separated from other vital tissues.

Patients are custom fit with the appropriately sized inner cup
Inner cup is joined via a silicone flange to a rigid outer cup containing an embedded stereotactic fiducial wire
Adhesive on the flange helps the device adhere to the patient
Attached suction pump evacuates the air from between the cups to provide a stable immobilization.
Clinical trials have found that prone positioning for breast cancer radiotherapy offers multiple benefits.1 The affected breast naturally falls away from chest wall and treatments can be designed to limit dose to the heart and lungs.
The GammaPod™ uses prone patient loaders in the imaging and treatment rooms to quickly and comfortably set up patients in the prone position. Providing reproducible setup at the time of imaging and treatment obviates the need for in-room image guidance.

Patients step onto the loader wearing the breast cup, which fits through an aperture in the couch and is securely docked in place
Smooth rotation of the couch seamlessly moves patients from the standing to prone position
For the Imager Loader, the CT table receives the couch and patient, which is then positioned for scanning
For the Treatment Loader, the GammaPod receives the couch and patient, which is then positioned for treatment.
The GammaPod™ treatment planning system (TPS) uses sophisticated Monte Carlo dose calculations, the gold standard in radiotherapy, to create a dynamic travel path along which the couch will during the delivery of the prescribed dose.
To accommodate the scan-plan-treat clinical workflow, the TPS provides clinicians with tools for quickly creating a new treatment plan each day based on changes to the target and anatomy.
Single-click localization of the stereotactic fiducial wire
Intuitive contouring tools for defining the GTV with interpolation between image slices
Easy creation of uniform margin expansion to define PTV
Rapid optimization based on plan goals
1/5
Workflow
4 Simple steps enabling Single-Day Adaptive Treatments
01
The noninvasive breast cup system, ad hoc immobilization and stereotactic localization system, is fitted to the patient.
The cup system is composed of a lightweight inner cup joined via a silicone flange to a rigid outer cup containing an embedded stereotactic fiducial wire.
Many cup sizes are available to better conform to the patient anatomy. Adhesive on the flange helps the device adhere to the patient.
Attached suction pump evacuates the air from between the cups creating a mild negative pressure, to move away the treatment area from the other tissues and minimize breast motion throughout imaging and treatment.
02
The breast cup system is locked to the imaging couch and the Imager Loader lifts and rotates from standing to prone position to quickly and comfortably set up patients on CT table.
To guarantee the absolute reproducibility of the setup the Imager Loader system exactly reflects the loading/unloading and the positioning of the patient in the treatment unit.
The images are acquired and sent to the Treatment Planning System.
03
TPS uses the embedded fiducials in the outer breast cup to register the images in the stereotactic coordinate system.
Clinicians contour the PTV and critical structures and enter the prescription.
TPS optimizes the dynamic travel path of the treatment table for coverage with high conformity and normal tissue sparing.
Resulting plan is approved for delivery.
04
Breast cup locks to treatment couch while patient stands on Treatment Loader.
Treatment Loader lifts, rotates patient to prone position over the GammaPod.
GammaPod treatment delivery: the system combines a continuously rotating 25-source irradiation unit with 15 mm and 25 mm collimators and 3D dynamic treatment table motion to enable the dose-painting to the target just as the dose distribution has been planned.
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Case Studies
The distinctive features of GammaPod™ help improve clinical outcomes and significantly reduce side effects.