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CRP Compact

CRP Compact is a unit for the automatic dispensing of radiopharmaceuticals and the automated sealing of open and closed vials under sterile conditions, in compliance with the provisions of EU GMP Annex 1.

Safe, compact, and extremely precise, the system allows for the dispensing of a wide range of radiopharmaceuticals, with no limits on concentration or volume, while minimizing operator intervention. It can handle both open and closed vials, as well as both crimped and push-fit caps.

The CRP Compact and the software that manages the interface are supplied fully validated from a pharmaceutical standpoint.

 

 

Used in contexts of:
Radiopharma Production

Designed and Manufactured by Tema Sinergie

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CRP Compact Automated Radiopharmaceutical Filling (7)

100+

Installed around the world

<1%

Volume (weight)

Open/Closed

Vial

EU A1

GMP

Overview

Designed for Your Process

CRP Compact is an automated radiopharmaceutical dispensing system designed to ensure accuracy, safety, and compliance with GMP requirements. Thanks to its high level of automation, it minimizes operator intervention and ensures reliable and repeatable processes.

Compact and versatile, it can handle various types of radiopharmaceuticals, vials, and closure systems, adapting to the needs of PET centers, nuclear medicine laboratories, and manufacturing facilities that require high quality and operational standards.

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CUSTOMIZABLE

Ability to develop customized process flows based on production needs through the integration of custom kits.

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PRECISE

Extremely high dispensing accuracy, with a volume (weight) deviation of less than 1%, thanks to the precision scale.

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MULTITRACER

It can process a very wide range of radiopharmaceuticals in vials in full compliance with the latest GMP specifications.

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VERSATILE

It allows you to work with most of the bottles available on the market, switching between different types within the same production cycle.

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NO VOLUME LIMIT

It allows you to handle bulk feed without volume or concentration limits and, at the same time, dispense both large volumes and microvolumes.

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AUTOMATIC

It automates the entire dispensing process, minimizing the need for manual intervention by the operator.

Compact dimensions

COMPACT

Thanks to its compact size, it can be installed in any type of laminar-flow shielded chamber equipped with a well for a calibrator and a remote gripper.

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FLEXIBLE SEALING

It can dispense into both open and closed bottles and can handle both push-fit caps and rubber stoppers with crimped aluminum rings.

overview

Two versions

Full adaptation to the production process.
CRP Compact Automated Radiopharmaceutical Filling (10)

CRP Compact

Optimized for dispensing radiopharmaceuticals from open vials, sealed with a rubber stopper and a crimped aluminum ring. With the addition of the piercing module, it can also be used with closed vials.

CRP Compact Automated Radiopharmaceutical Filling System (1)

CRP Compact Plus

Optimized for dispensing radiopharmaceuticals from open vials, sealed with a rubber stopper, a crimped aluminum ring, or a push-fit cap.

Workflow

Customized Four-Step Workflow

COMPLETE DISPENSING IN 4 STEPS

The dispensing process begins with the solution from the synthesis module and ends with a sealed vial containing the required volume and activity of the radiopharmaceutical.


FULL CUSTOMIZATION

The system’s configuration allows for the definition of customized process flows based on production needs, including through the integration of customized kits.

For this reason, CRP Compact is the ideal solution for all centers that need to implement specific workflows, such as CDMOs (Contract Development and Manufacturing Organizations).

Step 01

Measurement

Measurement of the activity sent to the synthesis module;

Step 02

Dilution

Dilution of the solution to the concentration required to begin the activity;

Step 03

Filling

Sterile filling of open or closed vials with volume control using a high-precision scale;

Step 04

Vial Closure

Close the tube once it is full

Features

CRP Compact is highly customizable to meet specific production needs, vial types, and capping strategies.

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Technical Specifications

Feature Value
Volumetric Accuracy (Weight) <1% (deviation)
Vial Compatibility Open / Closed (with piercing module)
Type of closure Crimp (stopper + ring), Push-fit
Dimensions and Weight 320 x 344 x 350 mm - 34 kg

Case Studies

Results in Real-World Settings

From the Clinic to Production: Case Studies Demonstrating Integration, Compliance, and Continuity.

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Services

Start a technical evaluation of the CRP Compact

Share your operating environment and key requirements: we’ll guide you toward the configuration that best suits your production process.
Quality and compliance are an integral part of how we work.

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Pre-Sales Services

Defining requirements, designing, and preparing for installation to reduce risks and operational variability.

  • Validation and qualification documentation
  • Installation and controlled commissioning
  • Operational training and procedures
Explore Our Pre-Sales Services
Icon Theme: Synergies

Pre-Sales Services

Defining requirements, designing, and preparing for installation to reduce risks and operational variability.

  • Validation and qualification documentation
  • Installation and controlled commissioning
  • Operational training and procedures
Explore Our Pre-Sales Services
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